Technician position – Start date Fall 2020

The Functional Cancer Genomics group directed by Prof. J.P. Theurillat at the Institute of Oncology Research in Bellinzona, Switzerland (http://www.ior.iosi.ch) is seeking a part- or full-time Technician in cancer research. The successful candidate will work as part of an international team that is dedicated to understanding how new driver alterations culled from cancer genome characterization studies promote tumorigenesis, and how gathered insights can be exploited to develop precision medic...
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IOR researchers suggest that androgen-deprivation treatments for prostate cancer could protect men from COVID-19

The so-called "androgen-deprivation" treatments used in prostate cancer therapy may have a protective effect against COVID-19. A study conducted by the Istitute of Oncology Research (IOR, affiliated to USI) based on health data obtained from the Veneto region in Italy has observed a lower risk of developing the coronavirus disease for men subject to this type of therapy. The study, performed in collaboration with the Institute for Research in Biomedicine (IRB, also affiliated to USI) and led by ...
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Postdoctoral fellow and PhD Student position Start date September 2020

A postdoctoral fellowship and a PhD student fellowship are available from September 2020 in the lab of Dr. Arianna Calcinotto at the international Institute of Oncology Research (IOR) that is affiliated toUSI - Università della Svizzera Italiana. The lab is embedded in a large and vibrant immunology community in the sunny part of Switzerland. The research interests of the lab are focused on cancer immunotherapy with a major goal of creatively approaching this problem to develop novel therapi...
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Tiziano Bernasocchi awarded “PhD in Life Sciences” from the University of Lausanne

Tiziano Bernasocchi, molecular biologist in the Prostate Cancer Genome group of Prof. Jean-Philippe Theurillat, successfully defended his Ph.D. on April 21st, 2020, from the University of Lausanne. He presented the work entitled: Dual Functions of SPOP and ERG Dictate Androgen Therapy Responses in Prostate Cancer.  The research work elucidates an enigmatic finding of comprehensive prostate cancer genome studies, namely that recurrent genetic rearrangements of the ERG transcription factor neve...
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Geniver El Tekle received the “PhD in Life Sciences” from the University of Lausanne

Geniver El Tekle successfully defended her Ph.D. thesis at the Institute of Oncology Research (IOR) in Bellinzona on April 20th, 2020. Her thesis entitled “ Functional Characterization and Therapeutic Implications of SPOP Mutations in Endometrial and Prostate Cancer” was carried out in the Functional Cancer Genomics group directed by Prof. Jean-Philippe Theurillat at the IOR.   The thesis focused on the role of missense mutations affecting the substrate-recognition domain of the ubiquitin lig...
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IOR paves the way for the clinical development of a therapy against prostate cancer metastasis

An international group of researchers, led by Andrea Alimonti, Group Leader at the Institute of Oncology Research (IOR, affiliated to USI) and Professor at the USI Faculty of Biomedical Sciences and at ETH Zurich, has discovered a mechanism to recognise the cancer cells responsible for prostate cancer and selectively eliminate them. The study was published on April 6 by the Journal of Clinical Investigation (JCI).   Background Prostate cancer is one of the most frequent causes of m...
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