Swiss Cancer Research grant to Dr. Luciano Cascione

Dr. Luciano Cascione, head of Bioinformatics Core Unit at the Institute of Oncology Research and at the Swiss Institute of Bioinformatics (SIB), has received a research grant by the Swiss Cancer Research to study an enigmatic and interesting class of non-coding RNA called ultra-conserved regions (UCRs) in B-cell lymphomas. UCRs are 100% identical (fully conserved) across human and rodent genomes suggesting an important evolutionarily conserved biological function. Using bioinformatic approaches coupled with RNA profiling, Dr. Luciano Cascione and his collaborators Dr Sara Napoli and Prof. Francesco Bertoni aim to describe the functional and relevant roles of UCRs in lymphoma diagnosis, prognosis, or treatment response.